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At fertilization, the Chinese scientist defends the creation of children edited by Jean

HThis phenomenon has been distinguished by a scientist widely used in the world's first gene-edited experiments and tweets with its audience – the media and a YouTube video – Wednesday by the International Human Genome Editing Summit.

"In this particular situation," Jiankyuki said of the twin girls born as a result of his work, "I'm proud." He also said that fellow scientists had begun a pregnancy in the early stages, along with the jerom-edited embryos as a "horrible activity".

More humorously began with his public advertisements about his research, Taking a silent gap from the audience, he said with a statement: "I want to apologize that these results have gone before settling down," he said.


In fact, his representatives arrived within a reporter of months and allowed extensive illustration in his lab to tell his story.

He was inaugurating the statement two days before the start of Oommen Chandy, who claims to have been born from genetic models by a few weeks ago. In an interview conducted by Associated Press, he interviewed and published in a news conference. Instead of publishing research in an academic journal, the Associated Press published a series of videos online. When he submitted his slides to Contributing Organizations in front of the Conference, they were not included in the pre-election process.

He admitted that his university was dark in what he was doing.

He also criticized several prominent scientists. David Baltimore of the California Institute of Technology said. After a 20-minute speech, he has been in the long Q & A session with the chairman of the organizing committee, "I do not think this is a transparent process." We only found them after the birth of their children. I think the lack of transparency will cause self-control of the scientific community. "

Why did he hide his job from the scientific community? "He asked. In 2017 he presented a speech at Cold Spring Harbor in the United States and spoke with the scientist at the University of California, Berkeley and the American morals. Only Berkeley scientist is the children of Jean.

He has now revealed that he has submitted a study to a journal. Until he was published, he refused to scrutinize the scientific community.

Births survived the conflicts between the news and the Western world. Because the major scientific organizations of the world have recognized. Such German editing results traditionally from the future generations of DNA. Genome editing technology is still relatively new, technical and security challenges. The DNA is undermining inadequate place

If he apologized for the "leak," he said that people with HIV / AIDS who are suffering from HIV / Aids have been breaking down on discrimination. It has also selected a CRRRR target for CRRPR target. When it is disabled, the cell reseter produces no HIV as a portal in the cells. People converted to CCR5 genes for HIV infection are preserved.

He will not always be convinced of his answers, reminding some scientists who leave politics on Sunday. He criticized David to lead a prominent producer of genetic editing equipment at Harvard University and to go through an "unintended medical treatment" (a HIV-preventable and treating) experiment. Her father, a HIV-positive father, realized that his father had a life-long life, including HIV. HIV has also identified some villages with a 30 per cent infection.

He speaks to Jiangguui in the International Human Genome Editing Summit in Hong Kong. Kin Chung / AP

"It's more sad and annoying now," says Liu, co-founder of Beam Therapytics, a gem making edition. "He was deeply concerned about the issues involved in his reactions, and I'm afraid that this field can be set up again [of therapeutic genome editing] Poor patients can not get the necessary treatment. "

Other viewers of the audience were equally criticized. "This is the way he said," he said, "but it was unnecessary and unnecessary," said the biosist Alta Charo of the Wisconsin University.

Most of the names were explained in his experiments in the techniques used in his techniques, mice and monkeys. When the fertilization ends, the most popular Genome editing; The sperm used to grow egg fertilizers has provided genome editing molecular CRISPR-Cas9 through micro-engineering. But the DNA The CRISPR's "multiple" vaccinations were needed to improve the efficiency of the edited edits to ensure that most cells in the edition should contain.

The DNA conception expert is a technique used to assess the uncertain genetic variation of CNNPR. When an editing correction finds an editable correction, he said, but it is unlikely to affect any biological activity. When the parents seem to be acceptable, they say, "The embryo has been selected to import this ebrahtism, and the alert after birth has not been confirmed by the off-target edition.

Successfully modified some cells of the fetus in the early stage. Others retain their original CCR5 gene, that is, they are not actually protected by HIV. Again, the parents said that they received "mosaicism" and that the quarries should be uncovered. Finally, the result of the CCR5 protein lost by five amino acids per edition. It is not clear if this is serious enough to disable the receptor and thus prevent the HIV infection.

The poet's attitude also angered his critics. Liu of Harvard said he would have to take an an Android tablet while he was fluent and said, "Training or any kind of training or any kind of scientific training is helpful.

There were many questions about the process he had taken to voluntarily obtain the parent's consent for the trial. He accepted that he had obtained consent from a married couple, not just the trained, professional or non-professional.

"Explaining the paragraph by line and paragraph to each family," I mean the meaning of the information, "he said, adding that he criticized patients for claiming that they were an AIDS vaccine and would like to" save the business secret of the project team.

"The chariot says that the AIDS vaccine trial trial claims that the patient had been given a misinterpreted epidemiology and that it was likely to be treated.

Eight couples went in for study, one was abandoned, he said. In each case, her father was HIV positive and was not a mother. In total, 31 embryos were injected. 70% have been edited.

A clinical trial to use the CIREIDI for deployment of CRRP 5 in human embryos was carried out, "to suspend due to the current situation." But it is very soon that the second mother is pregnant.

Lulu and Nana twins are healthy. "There will be a plan to monitor children for the next 18 years," he said, adding that they will admit to continuously monitoring and supporting adults.

The 34 protagonists did not provide any evidence to support Apple's claims in the story, so the talk was very eagerly waiting. Wherever twins are born, their family does not reveal where. He said that he had sought a moral approval from a board at the Harmony Men's Women and Children's Hospital in Shenhen. But this was one of the four embryos for research that led to birth. The girls were not born, the hospital authorities said.

Participants, dozen scientists and reporters installed a line at 500 auditorium gates on the morning of five in the morning at 7.30 am. Three hours before the session started – but there were 60 vacant seats in the room. In front of his session, three security officials were in front of the room with senior leaders. Photographers and other journalists broke the seat, filled the seat and sat on the seat. He's ahead).

Robin Lowell Budge, the development biologist at the Francis Crick Institute in London, says that the number of Britons is lesser than the start of the session. 5,000 have seen through webcasts.

"He needs to give me the opportunity to explain what he has done," said Lower-Badge, "if he had" careless behavior "in the discussion," we will soon end the session. "

Unlike the other speakers, sitting in the front lines, when they were talking to the platform, he turned away from one side of the door, handed the hand over his hand.

This week the use of genome editing in IVF embryos to the fetus is used for research in pregnancy. China's National Health Commission ordered the officials of Guangdong Province. He is currently investigating the research in the laboratory at Shenzhen. However, in China, he is not clear about the laws or guidelines he may violate. That's where genetic editing, human embryo research and controls in many other countries, in particular the US

Science University of Science and Technology, China has refused refusal to enter the university since the beginning of this year. He did not know anything about his research, "he said. Academic ethics,. "

He said that such research is "no". "I do not know why his experiment," he added. If he gets mere popularity then it will be his disgrace. So comprehensive investigation is essential.

She obtained her post-graduate degree from the University of Science and Technology at Hafeez in Anhui, Eastern Province. He returned to China in 2012 and joined the Southern University of the southern city of Shenzhen, China, where he worked as a postdoctoral collaborator at Stanford University Lab.

He attended the meeting and made a formal presentation. He also believed that editing was essential in the human embryo, even with his criticism. അടുത്തകാലത്തുണ്ടായ ബയോഎയ്റ്റിക്സ് റിപ്പോർട്ടുകളും അവസാനിച്ചു.

ഹാർവാർഡ് മെഡിക്കൽ സ്കൂളിന്റെ ഡീൻ ഡോക്ടർ ജോർജ് ഡാലി CRISPR ഭ്രൂണം എഡിറ്റിംഗിന്റെ "പ്രാക്റ്ററിയുടെ കഴിവിനെ വിലയിരുത്തുന്നതിനുള്ള മാനദണ്ഡങ്ങൾ" സ്ഥാപിക്കാൻ ആവശ്യപ്പെട്ടു. "വലതുപക്ഷം നൽകിയ വ്യക്തികൾ [to do this] വിദഗ്ധരായിരിക്കണം, പരിശീലനം നേടുക, "അദ്ദേഹം പറഞ്ഞു. പക്ഷേ, അദ്ദേഹം ചില അസഹിഷ്ണുതയെ പ്രകടിപ്പിച്ചു: "അത് മുന്നോട്ടു നീങ്ങാനുള്ള സമയമാണ് [debates about] ഈ സാങ്കേതികവിദ്യ മുന്നോട്ടു കൊണ്ടു പോകുന്നതിനായി ക്ലിനിക്കൽ പരിഭാഷയ്ക്ക് പാഥ് ഔട്ട് ചെയ്യാനുള്ള ധാർമിക അനുവാദം. "

അയാൾ അനധികൃതവും അനധികൃതവുമായ ക്രമരഹിതമായ ഗവേഷണത്തെക്കുറിച്ച് പരാമർശിച്ചുകൊണ്ട് ഡാലി ഇങ്ങനെ പറഞ്ഞു: "മനുഷ്യ ജർമ്മനിയുടെ എഡിറ്റിംഗ് മുന്നോട്ട് വന്നതായി, ഞങ്ങളുടെ കഴുത്ത് മണലിൽ വടിക്കരുത്. ഫീൽഡിന്റെ മാനദണ്ഡങ്ങൾക്കു വിരുദ്ധമായ ഒരു പ്രാക്ടീസ് ചെയ്യുന്നയാൾ സ്വയംനിയന്ത്രിതമായ ഒരു സ്വയംഭരണത്തെ പ്രതിഫലിപ്പിക്കുന്നതായി ഞാൻ കരുതുന്നില്ല. "

ഏതാനും മിനിട്ടുകൾക്കു ശേഷം, ജീവശാസ്ത്രജ്ഞനായ കാതി നികാൻ, ഭ്രൂണങ്ങളിൽ CRISPR-Cas9 ഉപയോഗത്തെക്കുറിച്ചുള്ള ഒരു വലിയ ചുവന്ന പതാക ഉയർത്തിയ പരീക്ഷണങ്ങൾ വിശദീകരിച്ചു. ചില ജീനുകൾ അപ്രാപ്തമാക്കുന്നതിനും അവർ ആദ്യകാല മനുഷ്യവികസനത്തിൽ അവർ വഹിക്കുന്ന പങ്ക് എന്താണെന്നറിയുന്നതിനും (ഐആർഎഫ് ഭ്രൂണങ്ങളിൽ ഗർഭിണികൾ സ്ഥാപിക്കാൻ ഉദ്ദേശമില്ലെങ്കിൽ) അവൾ ഈ സാങ്കേതികവിദ്യ ഉപയോഗിക്കുന്നു.

അവൾ അവതരിപ്പിച്ച പ്രസിദ്ധീകരിക്കാത്ത വിവരങ്ങളുടെ അടിസ്ഥാനത്തിൽ, "മെറ്റീരിയൽ സങ്കീർണ്ണതകളാണ്" എന്ന് ലാറ്റിൻ ലാറ്റിനിക്കെന്താണ് സൂചിപ്പിക്കുന്നത്. അതായത്, CRISPR-Cas9 അതുണ്ടാക്കിയ ജീനിലെത്താൻ സഹായിച്ചു, എന്നാൽ ഉദ്ദേശിച്ച എഡിറ്റിംഗിനൊപ്പം ഇത് വലിയ ഡിഎൻഎ ടാർഗെറ്റ് ചെയ്ത ജീൻ അടങ്ങിയിരിക്കുന്ന ക്രോമസോമിലെ (6, ഈ സാഹചര്യത്തിൽ) സെഗ്മെൻറുകളുടെ നഷ്ടം അല്ലെങ്കിൽ ലാഭം.

ഭ്രൂണഗണിതങ്ങൾ ജനിതകമാറ്റം വരുത്തിയതിന് ഇത് വളരെ പ്രധാനപ്പെട്ട ഒരു ജാഗ്രതയാണ്.

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